Publications

2024

Book chapter

Hybrid modeling of PEM fuel cell - machine learning of equilibrium water content within a 1D cell model

Golovin, Ievgen; Knoppe, Kilian; Kunde, Christian; Kienle, Achim

In: Computer aided chemical engineering - Amsterdam [u.a.] : Elsevier, Bd. 53 (2024), S. 151-156 [Symposium: 34th European Symposium on Computer Aided Process Engineering / 15th International Symposium on Process Systems Engineering, ESCAPE-34/PSE2024, Florence, Italy, 2-6 June 2024]

Mathematical modeling of an enzyme catalyzed transamination reaction with integrated product removal

Behrens, Jessica; Tiedemann, Sven; Langermann, Jan; Kienle, Achim

In: Computer aided chemical engineering - Amsterdam [u.a.] : Elsevier, Bd. 53 (2024), S. 721-726 [Symposium: 34th European Symposium on Computer Aided Process Engineering / 15th International Symposium on Process Systems Engineering, ESCAPE-34/PSE2024, Florence, Italy, 2-6 June 2024]

Multi-objective optimization of forced periodic operation of methanol synthesis in a fixed-bed reactor

Leiphold, Johannes; Nikolic, Daliborka; Seidel-Morgenstern, Andreas; Kienle, Achim

In: Computer aided chemical engineering - Amsterdam [u.a.] : Elsevier, Bd. 53 (2024), S. 1603-1608 [Symposium: 34th European Symposium on Computer Aided Process Engineering / 15th International Symposium on Process Systems Engineering, ESCAPE-34/PSE2024, Florence, Italy, 2-6 June 2024]

Dynamic modeling of particle size and porosity distribution in fluidized bed spray agglomeration

Otto, Eric; Dürr, Robert; Kienle, Achim; Bück, Andreas; Tsotsas, Evagelos

In: Computer aided chemical engineering - Amsterdam [u.a.] : Elsevier, Bd. 53 (2024), S. 163-168 [Symposium: 34th European Symposium on Computer Aided Process Engineering / 15th International Symposium on Process Systems Engineering, ESCAPE-34/PSE2024, Florence, Italy, 2-6 June 2024]

Improving the production of PHBV in cupriavidus necator by optimal control

Kok, Rudolph L., Johannes; Findeisen, Rolf; Kienle, Achim; Duvigneau, Stefanie

In: Computer aided chemical engineering - Amsterdam [u.a.] : Elsevier, Bd. 53 (2024), S. 2503-2508 [Symposium: 34th European Symposium on Computer Aided Process Engineering / 15th International Symposium on Process Systems Engineering, ESCAPE-34/PSE2024, Florence, Italy, 2-6 June 2024]

Peer-reviewed journal article

Moving horizon estimation and control of a binary simulated moving bed chromatographic processes with Langmuir isotherms

Chernev, Valentin Plamenov; Kienle, Achim; Wouwer, Alain Vande

In: Computers & chemical engineering - Amsterdam [u.a.] : Elsevier Science, Bd. 189 (2024), Artikel 108804

Dynamic mode decomposition based MPC of fluidized bed spray agglomeration

Otto, Eric; Dürr, Robert; Bück, Andreas; Kienle, Achim

In: IFAC-PapersOnLine / Internationale Förderung für Automatische Lenkung - Frankfurt : Elsevier, Bd. 58 (2024), Heft 14, S. 694-699

2023

Essay

Stability of combined continuous granulation and agglomeration processes in a fluidized bed with sieve-mill-recycle

Otto, Eric; Dürr, Robert; Kienle, Achim

In: Processes - Basel : MDPI, Bd. 11 (2023), insges. 13 S.

Book chapter

Towards machine learning of power-2-methanol processes

Martensen, Carl Julius; Plate, Christoph; Keßler, Tobias; Kunde, Christian; Kaps, Lothar; Kienle, Achim; Seidel-Morgenstern, Andreas; Sager, Sebastian

In: Computer aided chemical engineering - Amsterdam [u.a.] : Elsevier, Bd. 52 (2023), S. 561-568

Optimization of simulated moving bed chromatographic processes using surrogate models

Pishkari, Rojiar; Fechtner, Marcus; Keßler, Tobias; Kienle, Achim

In: Computer aided chemical engineering - Amsterdam [u.a.] : Elsevier, Bd. 52 (2023), S. 343-348

Modeling of particle formation in pan granulators with sieve-mill recycle

Dürr, Robert; Przywara, Mateusz; Otto, Eric Glende; Antos, Dorota; Kienle, Achim

In: Computer aided chemical engineering - Amsterdam [u.a.] : Elsevier, Bd. 52 (2023), S. 1027-1032

Modeling and experimental validation of poly(3-Hydroxybutyrate-co-3-hydroxyvalerate) chain length distribution

Duvigneau, Stefanie; Wilisch-Neumann, Annette; Dürr, Robert; Kienle, Achim

In: Computer aided chemical engineering - Amsterdam [u.a.] : Elsevier, Bd. 52 (2023), S. 2223-2228

Peer-reviewed journal article

Optimization of methanol synthesis under forced periodic operation in isothermal fixed-bed reactors

Leipold, Johannes; Seidel, Carsten; Nikolic, D.; Seidel-Morgenstern, Andreas; Kienle, Achim

In: Computers & chemical engineering - Amsterdam [u.a.] : Elsevier Science, Bd. 175 (2023), Artikel 108285

Nonlinear behavior of methanol synthesis compared to CO2 methanation

Leipold, Johannes; Jung, Magnus; Keßler, Tobias; Kienle, Achim

In: Chemical engineering & technology - Weinheim : Wiley-VCH Verl.-Ges. . - 2023, insges. 7 S.

Dissertation

Multiskalen-Modellierung der Polyhydroxyalkanoat-Biopolymer- und Influenza-A-Impfstoffproduktion

Duvigneau, Stefanie; Kienle, Achim

In: Magdeburg: Universitätsbibliothek, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Elektrotechnik und Informationstechnik 2023, 1 Online-Ressource (vi, 167 Seiten, 10,89 MB) [Literaturverzeichnis: Seite 149-166]

Modellierung und Optimierung erzwungener periodischer Betriebsweisen für die Methanolsynthese

Seidel, Carsten; Kienle, Achim

In: Magdeburg: Universitätsbibliothek, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Elektrotechnik und Informationstechnik 2023, 1 Online-Ressource (xxiii, 209 Seiten, 3,34 MB) [Literaturverzeichnis: Seite 191-203]

2022

Essay

Multiscale modeling of the microbial production of polyhydroxyalkanoates using two carbon sources

Duvigneau, Stefanie; Dürr, Robert; Wulkow, Michael; Kienle, Achim

In: Computers & chemical engineering - Amsterdam [u.a.] : Elsevier Science, Bd. 160 (2022), Artikel 107740, insges. 12 S.

Discrepancy-based control of particle processes

Otto, Eric; Behrens, Jessica; Palis, Stefan; Dürr, Robert; Kienle, Achim

In: Journal of process control - Amsterdam [u.a.] : Elsevier Science, Bd. 110 (2022), S. 99-109

Bifurcation analysis of combined agglomeration and layering granulation in fluidized bed spray processes

Otto, Eric; Dürr, Robert; Kienle, Achim

In: 32nd European Symposium on Computer Aided Process Engineering - San Diego : Elsevier ; Montastruc, Ludovic . - 2022, S. 691-696

Direct discretized kernel identification for continuous agglomeration processes

Otto, Eric; Maksakov, Anton; Dürr, Robert; Palis, Stefan; Kienle, Achim

In: IFAC-PapersOnLine / Internationale Förderung für Automatische Lenkung - Frankfurt : Elsevier, Bd. 55 (2022), Heft 7, S. 260-265

Book chapter

Integrated solvent and process design

Linke, Steffen; Keßler, Tobias; Kunde, Christian; Kienle, Achim; Sundmacher, Kai

In: Integrated Chemical Processes in Liquid Multiphase Systems - Berlin: De Gruyter; Kraume, Matthias . - 2022, S. 535-551

Global optimization for process design

Kunde, Christian; Kienle, Achim

In: Integrated Chemical Processes in Liquid Multiphase Systems - Berlin: De Gruyter; Kraume, Matthias . - 2022, S. 433-449

Deterministic global optimization of multistage layer melt crystallization using surrogate models and reduced space formulations

Kunde, Christian; Méndez, Ronald; Kienle, Achim

In: Konferenz: 32nd European Symposium on Computer Aided Process Engineering, Toulouse, 12.-15.06.2022, 32nd European Symposium on Computer Aided Process Engineering - San Diego: Elsevier; Montastruc, Ludovic . - 2022, S. 727-732

Peer-reviewed journal article

Forced periodic operations of a chemical reactor for methanol synthesis - the search for the best scenario based on Nonlinear Frequency Response method. Part I: Single input modulations

Nikolić, Daliborka; Seidel, Carsten; Felischak, Matthias; Miličić, Tamara; Kienle, Achim; Seidel-Morgenstern, Andreas; Petkovska, Menka

In: Chemical engineering science - Amsterdam [u.a.] : Elsevier Science, Bd. 248 (2022), Artikel 117134

Model Predictive Control of Simulated Moving Bed Chromatographic processes using Conservation Element/Solution Element method

Chernev, Valentin Plamenov; Santos, Lino O.; Wouver, Alain Vande; Kienle, Achim

In: IEEE Xplore digital library/ Institute of Electrical and Electronics Engineers - New York, NY: IEEE . - 2022, S. 355-361

Forced Periodic Operation of methanol synthesis in an isothermal gradientless reactor

Seidel, Carsten; Nikolić, Daliborka; Felischak, Matthias; Petkovska, Menka; Seidel-Morgenstern, Andreas; Kienle, Achim

In: Chemical engineering & technology - Weinheim: Wiley-VCH Verl.-Ges., Bd. 45 (2022), 12, S. 2261-2272

Wave reflections in counter-current separation processes with unequal mass transfer coefficients

Fechtner, Marcus; Kienle, Achim

In: Chemical engineering science - Amsterdam [u.a.]: Elsevier Science, Bd. 260 (2022)

Integrated computer-aided molecular and process design - green solvents for the hydroformylation of long-chain olefines

Keßler, Tobias; Kunde, Christian; Linke, Steffen; Sundmacher, Kai; Kienle, Achim

In: Chemical engineering science - Amsterdam [u.a.]: Elsevier Science, Bd. 249 (2022)

Forced periodic operations of a chemical reactor for methanol synthesis - the search for the best scenario based on Nonlinear Frequency Response method. Part II: Simultaneous modulation of two inputs

Nikolić, Daliborka; Seidel, Carsten; Felischak, Matthias; Miličić, Tamara; Kienle, Achim; Seidel-Morgenstern, Andreas; Petkovska, Menka

In: Chemical engineering science - Amsterdam [u.a.]: Elsevier Science, Bd. 248 (2022)

2021

Essay

Process behavior and product quality in fertilizer manufacturing using continuous hopper transfer pan granulation - experimental investigations

Przywara, Mateusz; Dürr, Robert; Otto, Eric; Kienle, Achim; Antos, Dorota

In: Processes - Basel : MDPI, Bd. 9 (2021), Heft 8, Artikel 1439, insges. 18 S.

Kernel identification in continuous fluidized bed spray agglomeration from steady state data

Otto, Eric; Dürr, Robert; Strenzke, Gerd; Palis, Stefan; Bück, Andreas; Tsotsas, Evangelos; Kienle, Achim

In: Advanced powder technology - Amsterdam [u.a.] : Elsevier - Vol. 31 (2021), insgesamt 13 Seiten

Multi-Rate data fusion for state and parameter estimation in (Bio-)chemical process engineering

Dürr, Robert; Duvigneau, Stefanie; Seidel, Carsten; Kienle, Achim; Bück, Andreas

In: Processes - Basel : MDPI, Bd. 9 (2021), Heft 11, Artikel 1990, insges. 16 S.

Fast, inexpensive, and reliable HPLC method to determine monomer fractions in poly(3-hydroxybutyrate-co-3-hydroxyvalerate)

Duvigneau, Stefanie; Kettner, Alexander; Carius, Lisa; Griehl, Carola; Findeisen, Rolf; Kienle, Achim

In: Applied microbiology and biotechnology - Berlin : Springer, Bd. 105 (2021), Heft 5, S. 4743-4749

Control of particle formation processes

Otto, Eric; Behrens, Jessica; Dürr, Robert; Palis, Stefan; Kienle, Achim

In: IFAC-PapersOnLine / Internationale Förderung für Automatische Lenkung - Frankfurt : Elsevier, Bd. 54 (2021), Heft 3, S. 231-236

Advanced kinetic modeling of bio-co-polymer poly(3-hydroxybutyrate-co-3-hydroxyvalerate) production using fructose and propionate as carbon sources

Duvigneau, Stefanie; Dürr, Robert; Behrens, Jessica; Kienle, Achim

In: Processes - Basel : MDPI, Bd. 9 (2021), Heft 8, Artikel 1260, insges. 19 S.

Book chapter

Hybrid cybernetic modeling of the microbial production of polyhydroxyalkanoates using two carbon sources

Duvigneau, Stefanie; Dürr, Robert; Kranert, Lena; Wilisch-Neumann, Annette; Carius, Lisa; Findeisen, Rolf; Kienle, Achim

In: 31th European Symposium on Computer Aided Process Engineering: ESCAPE-31 / edited by Metin Türkay and Rafiqul Gani: ESCAPE-31 - Amsterdam: Elsevier; Türkay, Metin - ESCAPE-31 . - 2021, S. 1969-1974

EXPERIMENTAL INVESTIGATION OF PROCESS BEHAVIOUR OF CONTINUOUS FLUIDIZED BED SPRAY AGGLOMERATION WITH INTERNAL CLASSIFICATION

Strenzke, Gerd; Dürr, Robert; Bück, Andreas; Kienle, Achim; Tsotsas, Evangelos

In: Proceedings of the13th International Conference on Fluidized Bed Technology , 2021 - Vancouver, Canada : GLAB Reactor and Fluidization Technologies ; Bi, Xiaotao, S. 374-379 [Konferenz: CFB 13, Vancouver, Canada, May 10-14, 2021]

Microbial production of polyhydroxyalkanoates - modeling of chain length distribution

Dürr, Robert; Duvigneau, Stefanie; Kienle, Achim

In: 31th European Symposium on Computer Aided Process Engineering: ESCAPE-31 / edited by Metin Türkay and Rafiqul Gani: ESCAPE-31 - Amsterdam: Elsevier; Türkay, Metin . - 2021, S. 1975-1982

Population balance modelling of pan granulation process

Otto, Eric; Dürr, Robert; Przywara, Mateusz; Antos, Dorota; Kienle, Achim

In: 31th European Symposium on Computer Aided Process Engineering: ESCAPE-31 / edited by Metin Türkay and Rafiqul Gani: ESCAPE-31 - Amsterdam: Elsevier; Türkay, Metin - ESCAPE-31 . - 2021, S. 965-970

Peer-reviewed journal article

Modelling and controlling of particle formation processes

Dürr, Robert; Otto, Eric; Kienle, Achim

In: Naukovi praci Donecʹkoho Nacionalʹnoho Techničnoho Universytetu / Problemi modeljuvannja ta avtomatizaciï proektuvannja/ Donec'kyj Nacional'nyj Techničnyj Universytet - Donecʹk, Bd. 17 (2021), 1, S. 66-72

Numerical short-cut design of simulated moving bed chromatography for multicomponent nonlinear adsorption isotherms - nonstoichiometric Langmuir model

Lee, Ju Weon; Kienle, Achim; Seidel-Morgenstern, Andreas

In: Industrial & engineering chemistry research - Columbus, Ohio: American Chemical Society, Bd. 60 (2021), 29, S. 10455-10834

Optimization of methanol synthesis under forced periodic operation

Seidel, Carsten; Nikolić, Daliborka; Felischak, Mattias; Petkovska, Menka; Seidel-Morgenstern, Andreas; Kienle, Achim

In: Processes: open access journal - Basel: MDPI - open access journal, Bd. 9 (2021), 5

Approximate shock layer solutions for the separation of multicomponent mixtures with different axial dispersion or mass transfer coefficients

Fechtner, Marcus; Kienle, Achim

In: Chemical engineering science - Amsterdam [u.a.]: Elsevier Science, Volume 231 (2021), article 116335

Dissertation

Model-based control for active damping of crane structural vibrations

Golovin, Ievgen; Kienle, Achim

In: Magdeburg, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Elektrotechnik und Informationstechnik 2021, ii, 129 Seiten [Literaturverzeichnis: Seite 115-123][Literaturverzeichnis: Seite 115-123]

2020

Essay

Hybrid cybernetic modeling of polyhydroxyalkanoate production in cupriavidus necator using fructose and acetate as substrates

Duvigneau, Stefanie; Dürr, Robert; Carius, Lisa; Kienle, Achim

In: IFAC-PapersOnLine / Internationale Förderung für Automatische Lenkung - Frankfurt : Elsevier, Bd. 53 (2020), Heft 2, S. 16872-16877

Model-based approach for predicting the impact of genetic modifications on product yield in biopharmaceutical manufacturing-Application to influenza vaccine production

Duvigneau, Stefanie; Dürr, Robert; Laske, Tanja; Bachmann, Mandy; Dostert, Melanie; Kienle, Achim

In: PLoS Computational Biology / Public Library of Science - San Francisco, Calif. : Public Library of Science - Volume 16 (2020), issue 6, article e1007810, 22 pages

Inferential control of product properties for fluidized bed spray granulation layering

Dürr, Robert; Neugebauer, Christoph; Palis, Stefan; Bück, Andreas; Kienle, Andreas

In: IFAC-PapersOnLine / Internationale Förderung für Automatische Lenkung - Frankfurt : Elsevier, Bd. 53 (2020), Heft 2, S. 11410-11415

Book chapter

Dynamics of spray granulation in continuously operated horizontal fluidized beds

Neugebauer, Christoph; Diez, Eugen; Mielke, Lisa; Palis, Stefan; Bück, Andreas; Tsotsas, Evangelos; Kienle, Achim; Heinrich, Stefan

In: Dynamic flowsheet simulation of solids processes - Cham : Springer Nature Switzerland AG 2020 ; Heinrich, Stefan, S. 67-107

Fast and accurate simulation of simulated moving bed chromatographic processes with linear adsorption isotherms

Pishkari, Rojiar; Kienle, Achim

In: 30th European Symposium on Computer Aided Chemical Engineering/ European Symposium on Computer Aided Chemical Engineering - Amsterdam: Elsevier, 2020; Pierucci, Sauro . - 2020, S. 487-492[Symposium: ESCAPE30, May 24-27, 2020, Milan, Italy]

Process control

Engell, Sebastian; Kienle, Achim

In: Preparative chromatography / edited by Henner Schmidt-Traub, Michael Schulte, Andreas Seidel-Morgenstern - Weinheim: Wiley-VCH, 2020 . - 2020, S. 504-524[Kapitel 9]

Methanol kinetics from optimal dynamic experiments

Seidel, Carsten; Kienle, Achim

In: 30th European Symposium on Computer Aided Chemical Engineering/ European Symposium on Computer Aided Chemical Engineering - Amsterdam: Elsevier, 2020; Pierucci, Sauro . - 2020, S. 7-12[Symposium: ESCAPE30, May 24-27, 2020, Milan, Italy]

Rational design of ion exchange simulated moving bed processes

Fechtner, Marcus; Kienle, Achim

In: 30th European Symposium on Computer Aided Chemical Engineering/ European Symposium on Computer Aided Chemical Engineering - Amsterdam: Elsevier; Pierucci, Sauro . - 2020, S. 733-738

Computer aided molecular design of green solvents for the hydroformylation of long-chain olefines

Keßler, Tobias; Kunde, Christian; Linke, Steffen; McBride, Kevin; Sundmacher, Kai; Kienle, Achim

In: 30th European Symposium on Computer Aided Process Engineering/ European Symposium on Computer Aided Process Engineering - Amsterdam: Elsevier, 2020 . - 2020, S. 745-750

Peer-reviewed journal article

Lyapunov-based online parameter estimation for continuous fluidized bed layering granulation

Otto, Eric; Neugebauer, Christoph; Palis, Stefan; Kienle, Achim

In: IFAC-PapersOnLine / Internationale Förderung für Automatische Lenkung - Frankfurt : Elsevier, Bd. 53 (2020), Heft 2, S. 11398-11403

On-line optimization of four-zone simulated moving bed chromatography using an equilibrium-dispersion model: I. Simulation study

Lee, Ju Weon; Kienle, Achim; Seidel-Morgenstern, Andreas

In: Chemical engineering science - Amsterdam [u.a.]: Elsevier Science, Volume 225 (2020), article 115810

Corrigendum to Kinetic modeling of methanol synthesis from renewable resources (Chem. Eng. Sci. 175 (2018), 130-138)

Seidel, Carsten; Jörke, A.; Vollbrecht, B.; Seidel-Morgenstern, Andreas; Kienle, Achim

In: Chemical engineering science - Amsterdam [u.a.]: Elsevier Science, Volume 223 (2020), article 115724

Efficient simulation of chromatographic processes using the conservation element/solution element method

Chernev, Valentin Plamenov; Wouwer, Alain Vande; Kienle, Achim

In: Processes: open access journal - Basel: MDPI, Vol. 8 (2020), 10, Artikelnr. 1316, insgesamt 19 Seiten[This article belongs to the Special Issue Advanced Methods in Process and Systems Engineering]

Using bifurcation theory for exploring pain

Verma, Parul; Kienle, Achim; Flockerzi, Dietrich; Ramkrishna, Doraiswami

In: Industrial & engineering chemistry research - Columbus, Ohio: American Chemical Society, Bd. 59.2020, 6, S. 2524-2535

Examining sodium and potassium channel conductances involved in hyperexcitability of chemotherapy-induced peripheral neuropathy - a mathematical and cell culture-based study

Verma, Parul; Eaton, Muriel; Kienle, Achim; Flockerzi, Dietrich; Yang, Yang; Ramkrishna, Doraiswami

In: Frontiers in computational neuroscience - Lausanne: Frontiers Research Foundation, Vol. 14 (2020), Article 564980

Computational analysis of a 9D model for a small DRG neuron

Verma, Parul; Kienle, Achim; Flockerzi, Dietrich; Ramkrishna, Doraiswami

In: Journal of computational neuroscience - Dordrecht [u.a.]: Springer Science + Business Media B.V, Bd. 48.2020, S. 429-444

On-line optimization of four-zone simulated moving bed chromatography using an Equilibrium-Dispersion Model: II. Experimental validation

Lee, Ju Weon; Kienle, Achim; Seidel-Morgenstern, Andreas

In: Chemical engineering science - Amsterdam [u.a.]: Elsevier Science, Volume 226 (2020), article 115808

Robust control of fluidized bed layering granulation

Neugebauer, Christoph; Seidel, Carsten; Palis, Stefan; Kienle, Achim

In: IFAC-PapersOnLine / Internationale Förderung für Automatische Lenkung - Frankfurt : Elsevier, Bd. 53 (2020), Heft 2, S. 11422-11427

Dissertation

Modeling and simulation of enzyme controlled metabolic networks using optimization based methods

Lindhorst, Henning; Kienle, Achim

In: Magdeburg, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Elektrotechnik und Informationstechnik 2020, III, 133 Seiten [Literaturverzeichnis: Seite 121-129][Literaturverzeichnis: Seite 121-129]

Modeling, dynamics and control of continuous fluidized bed layering granulation processes

Neugebauer, Christoph; Kienle, Achim; Palis, Stefan

In: Magdeburg, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Elektrotechnik und Informationstechnik 2020, xii, 139 Seiten [Literaturverzeichnis: Seite 121-131][Literaturverzeichnis: Seite 121-131]

2019

Essay

Lyapunov-based online parameter estimation in continuous fluidized bed spray agglomeration processes

Golovin, Ievgen; Otto, Eric Glende; Dürr, Robert; Palis, Stefan; Kienle, Achim

In: IFAC-PapersOnLine / Internationale Förderung für Automatische Lenkung - Frankfurt : Elsevier, Bd. 52 (2019), Heft 1, S. 329-334

Peer-reviewed journal article

Global optimization of distillation columns using explicit and implicit surrogate models

Keßler, Tobias; Kunde, Christian; McBride, Kevin; Mertens, Nick; Michaels, Dennis; Sundmacher, Kai; Kienle, Achim

In: Chemical engineering science - Amsterdam [u.a.]: Elsevier Science, Bd. 197 (2019), S. 235-245

Online estimation of optimal operating conditions for simulated moving bed chromatographic processes

Suvarov, Paul; Lee, Ju Weon; Vande Wouwer, Alain; Seidel-Morgenstern, Andreas; Kienle, Achim

In: Journal of chromatography / A - New York, NY [u.a.]: Science Direct, 1958, Bd. 1602.2019, S. 266-272

Systematic selection of green solvents and process optimization for the hydroformylation of long-chain olefines

Keßler, Tobias; Kunde, Christian; Linke, Steffen; McBride, Kevin; Sundmacher, Kai; Kienle, Achim

In: Processes - Basel: MDPI, Volume 7 (2019), 12, Artikel 882

Multi-mode model predictive control and estimation for uncertain biotechnological processes

Morabito, Bruno; Kienle, Achim; Findeisen, Rolf; Carius, Lisa

In: IFAC-PapersOnLine - Frankfurt: Elsevier, Bd. 52.2019, 1, S. 709-714[Part of special issue: 12th IFAC Symposium on Dynamics and Control of Process Systems, including Biosystems DYCOPS 2019: Florianópolis, Brazil, 2326 April 2019]

Surrogate modeling for liquidliquid equilibria using a parameterization of the binodal curve

Kunde, Christian; Keßler, Tobias; Linke, Steffen; McBride, Kevin; Sundmacher, Kai; Kienle, Achim

In: Processes - Basel: MDPI, Volume 7 (2019), 10, Artikel 753

On the dynamics and control of continuous fluidized bed layering granulation with screen-mill-cycle

Neugebauer, Christoph; Diez, Eugen; Bück, Andreas; Palis, Stefan; Heinrich, Stefan; Kienle, Achim

In: Powder technology - Amsterdam [u.a.] : Elsevier Science, Bd. 354 (2019), S. 765-778

Equilibrium theory of ion exchange chromatography with variable solution normality and steric hindrance

Fechtner, Marcus; Kienle, Achim

In: Chemical engineering science - Amsterdam [u.a.]: Elsevier Science, Bd. 199 (2019), S. 508-527

Dissertation

Mathematische Modellierung und Simulation von in-silico Protozellen nach dem Modularisierungs- und Baukastenprinzip

Schneider, Eugenia; Kienle, Achim

In: Magdeburg, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Elektrotechnik und Informationstechnik 2019, xiv, 115 Seiten [Literaturverzeichnis: Seite 103-115][Literaturverzeichnis: Seite 103-115]

Discrete modeling of drying induced ion transport and crystallization in porous media

Rahimi, Arman; Tsotsas, Evangelos; Kienle, Achim

In: Magdeburg, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Verfahrens- und Systemtechnik 2019, xv, 153 Seiten [Literaturverzeichnis: Seite 117-127][Literaturverzeichnis: Seite 117-127]

2018

Essay

Parameter identification for continuous fluidized bed spray agglomeration

Golovin, Ievgen; Strenzke, Gerd; Dürr, Robert; Palis, Stefan; Bück, Andreas; Tsotsas, Evangelos; Kienle, Achim

In: Processes - Basel : MDPI - Vol. 6.2018, 12, Artikel 246

Book chapter

Influence of drying conditions on process properties and parameter identification for continuous fluidized bed spray agglomeration

Strenzke, Gerd; Golovin, Ievgen; Wegner, M.; Palis, Stefan; Bück, Andreas; Kienle, Achim; Tsotsas, Evangelos

In: IDS 2018 / International Dryign Symposium , .2018 - València, Spain : Universitat ; Cárcel, Juan Andrés, S. 579-586

Influence of thermal conditions on particle properties in fluidized bed layering granulation

Neugebauer, Christoph; Bück, Andreas; Palis, Stefan; Mielke, Lisa; Tsotsas, Evangelos; Kienle, Achim

In: 6th International Conference on Population Balance Modelling - Ghent, Belgium : Ghent University . - 2018, insges. 8 S.

Kinetic modeling of methanol synthesis - impact of catalyst deactivation

Seidel, Carsten; Jörke, Andreas; Vollbrecht, Bert; Seidel-Morgenstern, Andreas; Kienle, Achim

In: Computer aided chemical engineering - Amsterdam [u.a.]: Elsevier, Bd. 43.2018, S. 85-90[Symposium: 28th European Symposium on Computer Aided Process Engineering, Graz, Austria, 10-13 June 2018]

Efficient simulation of ion exchange chromatography with application to bioseparations

Fechtner, Marcus; Kaspereit, Malte; Kienle, Achim

In: Computer aided chemical engineering - Amsterdam [u.a.]: Elsevier, Bd. 43 (2018), S. 295-300

Parameter identification for continuous fluidized bed spray agglomeration

Golovin, Ivgen; Strenzke, Gerd; Wegner, Maximilian; Palis, Stefan; Bück, Andreas; Kienle, Achim; Tsotsas, Evangelos

In: 6th International Conference on Population Balance Modelling - Ghent, Belgium : Ghent University . - 2018, insges. 4 S.

Peer-reviewed journal article

Mathematical modeling as a tool to improve influenza vaccine production processes

Duvigneau, Stefanie; Dürr, Robert; Laske, Tanja; Bachmann, Mandy; Dostert, Melanie; Reichl, Udo; Kienle, Achim

In: IFAC-PapersOnLine / Internationale Förderung für Automatische Lenkung - Frankfurt : Elsevier , 2015, Bd. 51 (2018), Heft 19, S. 1-4

Influence of thermal conditions on particle properties in fluidized bed layering granulation

Neugebauer, Christoph; Bück, Andreas; Palis, Stefan; Mielke, Lisa; Tsotsas, Evangelos; Kienle, Achim

In: Processes - Basel : MDPI - Vol. 6.2018, 12, Artikel 235

Model-based state estimation based on hybrid cybernetic models

Carius, Lisa; Pohlodek, J.; Morabito, Bruno; Franz, A.; Mangold, M.; Findeisen, Rolf; Kienle, Achim

In: IFAC-PapersOnLine - Frankfurt: Elsevier, Bd. 51.2018, 18, S. 197-202[Symposium: 10th IFAC Symposium on Advanced Control of Chemical Processes, ADCHEM 2018, Shenyang, China, 25-27 July 2018]

Global optimization of distillation columns using surrogate models

Keßler, Tobias; Kunde, Christian; Mertens, Nick; Michaels, Dennis; Kienle, Achim

In: SN applied sciences - [Cham]: Springer International Publishing, Vol. 1.2019, Artikel 27, 2018

Global optimization of multistage binary separation networks

Kunde, Christian; Kienle, Achim

In: Chemical engineering and processing - Amsterdam [u.a.]: Elsevier, Bd. 131.2018, S. 164-177

Monotonic reformulation and bound tightening for global optimization of ideal multi-component distillation columns

Mertens, Nick; Kunde, Christian; Kienle, Achim; Michaels, Dennis

In: Optimization and engineering: international multidisciplinary journal to promote optimizational theory & applications in engineering science - Dordrecht [u.a.]: Springer Science + Business Media B.V, Bd. 19.2018, 2, S. 479-514

Efficient simulation and equilibrium theory for adsorption processes with implicit adsorption isotherms - ideal adsorbed solution theory

Fechtner, Marcus; Kienle, Achim

In: Chemical engineering science - Amsterdam [u.a.]: Elsevier Science, Bd. 177 (2018), S. 284-292

Kinetic modeling of methanol synthesis from renewable resources

Seidel, Carsten; Jörke, A.; Vollbrecht, B.; Seidel-Morgenstern, Andreas; Kienle, Achim

In: Chemical engineering science - Amsterdam [u.a.]: Elsevier Science, Bd. 175.2018, S. 130-138

Dissertation

Dynamic methods for thermodynamic equilibrium calculations in process simulation and process optimization

Zinser, Alexander; Sundmacher, Kai; Kienle, Achim

In: Magdeburg, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Verfahrens- und Systemtechnik 2018, xvi, 128 Seiten [Literaturverzeichnis: Seite 117-125][Literaturverzeichnis: Seite 117-125]

Scientific monograph

Magdeburger Automatisierungstechnik im Wandel - vom Industrie- zum Forschungsstandort

Neumann, Peter; Diedrich, Christian; Höltge, Rolf; Jumar, Ulrich; Kienle, Achim; Krampitz, Reinhold; Müller, Günter; Pusch, Konrad; Rokosch, Helga; Schmidt, Barbara; Schmucker, Ulrich; Unger, Gerhard; Wolf, Günter

In: Magdeburg: Otto-von-Guericke-Universität, 2018, 223 Seiten, ISBN: 978-3-944722-75-7

2017

Essay

Control of continuous mixed-solution mixed-product removal crystallization processes

Geyyer, Rostyslav; Dürr, Robert; Temmel, Erik; Li, Tao; Lorenz, Heike; Palis, Stefan; Seidel-Morgenstern, Andreas; Kienle, Achim

In: Chemical engineering & technology - Weinheim : Wiley-VCH Verl.-Ges., Bd. 40 (2017), Heft 7, S. 1362-1369

Book chapter

Process dynamics of continuous fluidised bed layering granulation

Bück, Andreas; Schmidt, Martin; Neugebauer, Christoph; Palis, Stefan; Kienle, Achim; Heinrich, Stefan; Tsotsas, Evangelos

In: 8th International Granulation Workshop: Sheffield, UK, June 2017- Sheffield, 2017, Posternr. 2, paper 67, insgesamt 5 Seiten[Beitrag auf USB-Stick]

Global optimization of distillation columns using surrogate models

Keßler, Tobias; Kunde, Christian; Mertens, Nick; Michaels, Dennis; Kienle, Achim

In: Evolutionary and deterministic methods for design optimization and control with applications to industrial and societal problems : Sep 13-15, 2017 in Madrid, Spain ; EUROGEN 2017 ; Book of abstracts - Madrid : Technical University - 2017, paper 041, insgesamt 7 Seiten

Online parameter identification for continuous fluidized bed spray granulation with external sieve-mill cycle

Palis, Stefan; Kienle, Achim

In: IEEE Xplore digital library / Institute of Electrical and Electronics Engineers - New York, NY : IEEE . - 2017, S. 594-598

Efficient global optimization of a novel hydroformylation process

Keßler, Tobias; Mertens, Nick; Kunde, Christian; Nentwich, Corina; Michaels, Dennis; Kienle, Achim

In: 27th European symposium on computer aided process engineering - Amsterdam : Elsevier ; Espuña, Antonio . - 2017, S. 2113-2118

Peer-reviewed journal article

Efficient simulation and equilibrium theory for adsorption processes with implicit adsorption isotherms - mass action equilibria

Fechtner, Marcus; Kienle, Achim

In: Chemical engineering science - Amsterdam [u.a.] : Elsevier Science, Bd. 171 (2017), S. 471-480

A dynamic two-zone model of continuous fluidized bed layering granulation with internal product classification

Neugebauer, Christoph; Palis, Stefan; Bück, Andreas; Tsotsas, Evangelos; Heinrich, Stefan; Kienle, Achim

In: Particuology - Amsterdam: Elsevier, Bd. 31.2017, S. 8-14

Dissertation

Global optimization in conceptual process design

Kunde, Christian; Kienle, Achim; Seidel-Morgenstern, Andreas

In: Magdeburg, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Elektrotechnik und Informationstechnik 2017, i, 123 Seiten, Illustrationen [Literaturverzeichnis: Seite 117-123]

Analysis and design of center-cut separations using 8-zone simulated moving bed chromatography

Santos da Silva, Francisco Vitor; Kienle, Achim; Seidel-Morgenstern, Andreas

In: Magdeburg, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Verfahrens- und Systemtechnik 2017, 161 Seiten, Illustrationen, Diagramme, 30 cm [Literaturverzeichnis: Seite 142-153]

Investigating arsenic and osmotic stress response in yeast saccharomyces cerevisiae using mathematical modeling and model selection

Rastgou Talemi, Soheil; Kienle, Achim

In: Magdeburg, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Elektrotechnik und Informationstechnik 2016, XII, 124 Seiten, Illustrationen, Diagramme, 21 cm

2016

Book chapter

A reformulation strategy for deterministic global optimization of ideal multi-component distillation processes

Mertens, Nick; Kunde, Christian; Kienle, Achim; Michaels, Dennis

In: Computer aided chemical engineering- Amsterdam [u.a.]: Elsevier, 1997, Bd. 38.2016, S. 691-696[Kongress: 26th European Symposium on Computer Aided Process Engineering]

Influence of mill characteristics on stability of continuous layering granulation with external product classification

Neugebauer, Christoph; Palis, Stefan; Bück, Andreas; Diez, Eugen; Heinrich, Stefan; Tsotsas, Evangelos; Kienle, Achim

In: Computer aided chemical engineering - Amsterdam [u.a.]: Elsevier, 1997, Bd. 38.2016, S. 1275-1280[Kongress: 26th European Symposium on Computer Aided Process Engineering]

Control of MSMPR crystallization processes

Geyyer, Rostyslaw; Dürr, Robert; Temmel, E.; Li, T.; Lorenz, H.; Palis, Stefan; Seidel-Morgenstern, Andreas; Kienle, Achim

In: BIWIC 2016 : 23rd International Workshop on Industrial Crystallization, September 6-8, 2016, Max Planck Institute for Dynamics of Complex Technical Systems Magdeburg - Germany. - Göttingen : Cuvillier Verlag, S. 335-341[Kongress: 23rd International Workshop on Industrial Crystallization, BIWIC 2016, Magdeburg, 6-8 September, 2016]

Peer-reviewed journal article

Modeling and simulation of particulate processes

Kienle, Achim; Palis, Stefan; Mangold, Michael; Dürr, Robert

In: Ėlektronnoe modelirovanie - Kiev : Naukova Dumka, Bd. 38 (2016), Heft 5, S. 23-34

Untersuchung des dynamischen Verhaltens der Sprühgranulation in kontinuierlich betriebenen Wirbelschichtrinnen

Diez, E.; Heinrich, S.; Meyer, Katja; Tsotsas, Evangelos; Neugebauer, C.; Kienle, Achim

In: Chemie - Ingenieur - Technik: CIT- Weinheim: Wiley-VCH Verl, 1949, Bd. 88.2016, 9, S. 1359-1360[Special Issue: ProcessNet-Jahrestagung und 32. DECHEMA-Jahrestagung der Biotechnologen 2016]

Analyzing the impact of heterogeneity in genetically engineered cell lines for influenza vaccine production using population balance modeling

Dürr, Robert; Duvigneau, Stefanie; Laske, Tanja; Bachmann, Mandy; Kienle, Achim

In: IFAC-PapersOnLine / Internationale Förderung für Automatische Lenkung - Frankfurt : Elsevier , 2015, Bd. 49 (2016), Heft 26, S. 225-230

An efficient approximate moment method for multi-dimensional population balance models - application to virus replication in multi-cellular systems

Dürr, Robert; Müller, Thomas; Duvigneau, Stefanie; Kienle, Achim

In: Chemical engineering science- Amsterdam [u.a.]: Elsevier Science, 1951, 2016

Influence of operation parameters on process stability in continuous fluidised bed layering with external product classification

Bück, Andreas; Neugebauer, Christoph; Meyer, Katja; Palis, Stefan; Diez, Eugen; Kienle, Achim; Heinrich, Stefan; Tsotsas, Evangelos

In: Powder technology: an international journal on the science and technology of wet and dry particulate systems - Amsterdam [u.a.]: Elsevier Science, 1967, Bd. 300.2016, S. 37-45[Kongress: 7th International Granulation Workshop 2015: Granulation across the length scales]

Deterministic global optimization in conceptual process design of distillation and melt crystallization

Kunde, Christian; Michaels, Dennis; Micovic, Jovana; Lutze, Philip; Górak, Andrzej; Kienle, Achim

In: Chemical engineering and processing- Amsterdam [u.a.]: Elsevier, 1984, Bd. 99.2016, S. 132-142

Control of incomplete separation in simulated moving bed chromatographic processes

Suvarov, Paul; Wouwer, Alain; Wouwer, Alain vande; Lee, Ju Weon; Seidel-Morgensten, Andreas; Kienle, Achim

In: IFAC-PapersOnLine - Frankfurt: Elsevier, Bd. 49.2016, 7, S. 153-158, 49 2016 7 153-158[Kongress: 11th IFAC Symposium on Dynamics and Control of Process SystemsIncluding Biosystems, DYCOPS-CAB 2016, Trondheim, Norway, 6-8 June, 2016]

Dissertation

Robuste Regelung von Simulated Moving Bed Chromatographieprozessen

Suvarov, Paul; Kienle, Achim

In: Magdeburg, 2016, 114 Seiten, Illustrationen[Literaturverzeichnis: Seite 104-107; englischer Titel: Robust control methods for Simulated Moving Bed chromatographic separation processes]

Modellbasierte Bestimmung von Interventionsstrategien zur Optimierung der Produktion von Biokraftstoffen in Cyanobakterien

Erdrich, Philipp; Reichl, Udo; Kienle, Achim

In: Magdeburg, 2016, xx, 158 Seiten, Illustrationen

Modellbasierte Analysen zur Gestaltung und Betriebsführung von Biogasanlagen

Bensmann, Astrid Lilian; Sundmacher, Kai; Kienle, Achim

In: München, Dr. Hut, 2016, xiv, 149 Seiten, Illustrationen, 21 cm x 14.8 cm, 280 g - (Verfahrenstechnik)[Literaturverzeichnis: Seite 135-144]

Parameter estimation and method of moments for multi dimensional population balance equations with application to vaccine production processes

Dürr, Robert; Kienle, Achim; Thévenin, Dominique

In: Magdeburg, 2016, ii , 151 Seiten, Illustrationen[Literaturverzeichnis: Seite 141-150]

Development of an efficient method for simulating fixed-bed adsorption dynamics using Ideal Adsorbed Solution Theory

Rubiera Landa, Héctor Octavio; Kienle, Achim

In: Magdeburg, 2016, xxii, 227 Seiten, Illustrationen[Literaturverzeichnis: Seite 195-222]

Article in conference proceedings

Analyzing the impact of heterogeneity in genetically engineered cell lines for influenza vaccine production using population balance modeling

Dürr, Robert; Duvigneau, Stefanie; Laske, Tanja; Bachmann, Mandy; Kienle, Achim

In: FOSBE 2016: 6th International Conference on Foundations of Systems Biology in Engineering Magdeburg, Germany, October 9-12,2016 : program booklet - Magdeburg, 2016; Findeisen, Rolf, 2016, Art. TuPP.1, S. 32[Kongress: 6th International Conference on Foundations of Systems Biology in Engineering, FOSBE 2016, Magdeburg, Germany, October 9-12,2016]

Control of multi-chamber continuous fluidized bed spray granulation

Palis, Stefan; Neugebauer, Christoph; Bück, Andreas; Heinrich, Stefan; Tsotsas, Evangelos; Kienle, Achim

In: PARTEC 2016: International Congress on Particle Technology : April 19-21, 2016, Nürnberg, Germany - Nürnberg, 2016 . - 2016, insges. 4 S.[Beitrag auf USB-Stick]

2015

Essay

Online parameter identification of facet growth kinetics in crystal morphology population balance models

Dürr, Robert; Palis, Stefan; Kienle, Achim

In: Procedia engineering - Amsterdam [u.a.] : Elsevier, Bd. 102 (2015), S. 1336-1345

Efficient DQMOM for multivariate population balance equations and application to virus replication in cell cultures

Dürr, Robert; Müller, Thomas; Kienle, Achim

In: 8th Vienna International Conference on Mathematical Modelling 2015 - IFAC ; Breitenecker, Felix, S. 29-34

Book chapter

Deterministic global optimization of multistage melt crystallization processes in hydroformylation

Kunde, Christian; Kienle, Achim

In: 12th International Symposium on Process Systems Engineering and 25th European Symposium on Computer Aided Process Engineering - Amsterdam [u.a.] : Elsevier . - 2015, S. 1061-1066 - (Computer-aided chemical engineering; 37)

Peer-reviewed journal article

Robust control of continuous crystallization processes

Geyyer, Rostyslav; Kienle, Achim; Palis, Stefan

In: IFAC-PapersOnLine. - Frankfurt : Elsevier, Bd. 48.2015, 11, S. 598-603[Kongress: 1st IFAC Conference on Modelling, Identification and Control of Nonlinear Systems MICNON 2015, Saint Petersburg, Russia, 24-26 June 2015]

Combination of limited measurement information and multidimensional population balance models

Dürr, Robert; Franz, André; Kienle, Achim

In: IFAC-PapersOnLine/ Internationale Förderung für Automatische Lenkung - Frankfurt: Elsevier, Bd. 48 (2015), Heft 20, S. 261-166

Auto-tuning control systems for improved operation of continuous fluidized bed spray granulation processes with external product classification

Palis, Stefan; Dreyschultze, Christian; Neugebauer, Christoph; Kienle, Achim

In: Procedia engineering - Amsterdam [u.a.]: Elsevier, 2009, Bd. 102.2015, S. 133-141

Entropy-based control of continuous Fluidized bed spray granulation processes

Palis, Stefan; Bück, Andreas; Kienle, Achim

In: IFAC-PapersOnLine. - Frankfurt : Elsevier, Bd. 48.2015, 13, S. 154-157[Kongress: 5th IFAC Workshop on Lagrangian and Hamiltonian Methods for Nonlinear Control LHMNC 2015, Lyon, France, 4-7 July 2015]

Influence of zone formation on stability of continuous fluidized bed layering granulation with external product classification

Dreyschultze, Christian; Neugebauer, Christoph; Palis, Stefan; Bück, Andreas; Tsotsas, Evangelos; Heinrich, Stefan; Kienle, Achim

In: Particuology - Amsterdam: Elsevier, 2008, Bd. 23.2015, S. 1-7

Deterministic global optimization of binary hybrid distillation/melt-crystallization processes based on relaxed MINLP formulations

Ballerstein, Martin; Kienle, Achim; Kunde, Christian; Michaels, Dennis; Weismantel, Robert

In: Optimization and engineering: international multidisciplinary journal to promote optimizational theory & applications in engineering science - Dordrecht [u.a.]: Springer Science + Business Media B.V, Bd. 16.2015, 2, S. 409-440

Dissertation

Nonlinear dynamics of Poly(hydroxyalkanoate) production in Ralstonia eutropha and Rhodospirillum rubrum

Franz, André; Kienle, Achim

In: Magdeburg, Univ., Fak. für Elektrotechnik und Informationstechnik, Diss., 2015, XIX, 134 S., graph. Darst.

Article in conference proceedings

Influence of operation parameters onprocess stability in conzinuous fluidised bed layering with external classification

Bück, Andreas; Neugebauer, Christoph; Meyer, Katja; Palis, Stefan; Diez, Eugen; Kienle, Achim; Heinrich, Stefan; Tsotsas, Evangelos

In: 7th International Granulation Workshop: Sheffield, UK, 2015 - Sheffield, 2015 . - 2015, insges. 11 S.[Beitrag auf USB-Stick]

2014

Essay

Population balance modeling of biopolymer production in cellular systems (I)

Franz, André; Dürr, Robert; Kienle, Achim

In: Proceedings of the 19th IFAC world congress 2014 - IFAC ; Boje, Edward, S. 1705-1710 Kongress: IFAC World Congress 19 Cape Town, South Africa 2014.08.24-29

An efficient method for calculating the moments of multidimensional growth processes in population balance systems

Dürr, Robert; Kienle, Achim

In: The Canadian journal of chemical engineering - Ottawa, Ontario : Soc., Bd. 92 (2014), Heft 12, S. 2088-2097

Book chapter

Auto-tuning of multivariable PI/PID controllers using iterative feedback tuning - design examples

Sommer, Steffen; Nguyen, Hoang; Kienle, Achim

In: 24th European Symposium on Computer Aided Process Engineering ; Pt. A - Amsterdam [u.a.]: Elsevier, 2014; Pt. A . - 2014, S. 721-726 - (Computer-aided chemical engineering; 33)Kongress: ESCAPE 24 (Budapest, Hungary : 2014.06.15-18)

A methodology for experimental determination of stability boundaries with application to fluidized bed spray granulation

Palis, Stefan; Dreyschultze, Christian; Kienle, Achim

In: Computer aided chemical engineering. - Amsterdam [u.a.] : Elsevier, Bd. 33.2014, S. 625-630

Discrepancy-based control of a heat equation with quadratic nonlinearity

Palis, Stefan; Kienle, Achim

In: American Control Conference (ACC), 2014. - Piscataway, NJ : IEEE, S. 3359-3362Kongress: ACC; (Portland, Or.) : 2014.06.04-06

Stability analysis of switching hyperbolic systems - the example of SMB chromatography

Bastin, Georges; Coron, Jean-Michel; d'Andréa-Novel, Brigitte; Suvarov, Paul; Wouwer, Alain Vande; Kienle, Achim

In: European Control Conference (ECC), 2014: 24 - 27 June 2014, Strasbourg, France - Piscataway, NJ: IEEE, S. 2153 - 2157Kongress: ECC (Strasbourg, France : 2014.06.24-27)

Peer-reviewed journal article

Discrepancy based control of particulate processes

Palis, Stefan; Kienle, Achim

In: Journal of process control. - Amsterdam [u.a.] : Elsevier Science, Bd. 24.2014, 3, S. 33-46

Coupled continuous chromatography and racemization processes for the production of pure enantiomers

Swernath, Subramanian; Kaspereit, Malte; Kienle, Achim

In: Chemical engineering & technology. - Weinheim : Wiley-VCH Verl.-Ges, Bd. 37.2014, 4, S. 643-651

Cycle to cycle adaptive control of simulated moving bed chromatographic separation processes

Suvarov, Paul; Kienle, Achim; Nobre, Clarisse; Weireld, Guy; Vande Wouwer, Alain

In: Journal of process control: a journal affiliated with IFAC, the International Federation of Automatic Control - Amsterdam [u.a.]: Elsevier Science, Bd. 24.2014, 2, S. 357-367

Evaluation of multipoint dosing strategy in a miniaturized tubular reactor - nitration of salicylic acid

Debnath, Soujoy; Kienle, Achim; Kulkarni, Amol A.

In: Chemical engineering & technology. - Weinheim : Wiley-VCH Verl.-Ges, Bd. 37.2014, 6, S. 927-937

Development and nonlinear analysis of dynamic plant models in ProMot /Diana

Mangold, Michael; Khlopov, Dmytro; Danker, Gerrit; Palis, Stefan; Svjatnyj, Volodymyr; Kienle, Achim

In: Chemie - Ingenieur - Technik. - Weinheim : Wiley-VCH Verl, Bd. 86.2014, 7, S. 1107-1116

Dissertation

Optimal experimental design for parameter identification and model selection

Schenkendorf, René; Mangold, Michael; Kienle, Achim

In: Magdeburg, Univ., Fak. für Elektrotechnik und Informationstechnik, Diss., 2014, XII, 159 S.

Modellbasierte Identifizierung von Interventionsstrategien für Stoffwechselnetzwerke

Hädicke, Oliver; Kienle, Achim

In: Magdeburg Univ., Fak. für Elektrotechnik und Informationstechnik, Diss., 2014, IV, 169 S., graph. Darst., 30 cm

2013

Essay

Distributed modeling of human influenza a virus–host cell interactions during vaccine production

Müller, Thomas; Dürr, Robert; Isken, Britta; Schulze-Horsel, Josef; Reichl, Udo; Kienle, Achim

In: Biotechnology & bioengineering - New York, NY [u.a.] : Wiley, Bd. 110 (2013), Heft 8, S. 2252-2266

Book chapter

Adaptice discrepancy based control of continuous fluidized bed spray granulation with internal classification

Palis, Stefan; Bück, Andreas; Kienle, Achim

In: 9th IFAC Symposium on Nonlinear Control Systems 2013. - Elsevier, S. 400-405Kongress: IFAC Symposium on Nonlinear Control Systems; 9 (Toulouse, France); : 2013.09.04-06

Population balance modeling of crystallization in a fluidized bed

Palis, Stefan; Binev, D.; Lorenz, H.; Seidel-Morgenstern, Andreas; Kienle, Achim

In: BIWIC 2013. - Odense : Univ. of Southern Denmark, S. 252-259Kongress: BIWIC; 20 (Odense, Denmark) : 2013.09.18-20

Peer-reviewed journal article

H∞ loop shaping control for continuous fluidized bed spray granulation with internal product classification

Palis, Stefan; Kienle, Achim

In: Industrial & engineering chemistry research. - Columbus, Ohio : American Chemical Society, Bd. 52.2013, 1, S. 408-420

Dynamics and control of coupled continuous chromatography and crystallization processes for the production of pure enantiomers

Swernath, S.; Kaspereit, M.; Kienle, Achim

In: Chemical engineering & technology. - Weinheim : Wiley-VCH Verl.-Ges, Bd. 36.2013, 8, S. 1417-1429

Spectral properties of Bi-Langmuir isotherms

Flockerzi, D.; Kaspereit, M.; Kienle, Achim

In: Chemical engineering science. - Amsterdam [u.a.] : Elsevier Science, Bd. 104.2013, S. 957-959

Article in conference proceedings

A plug and control strategy for simulated moving bed processes - stability analysis

Suvarov, Paul; Wouwer, Alain Vande; Kienle, Achim

In: 32st Benelux Meeting on Systems and Control. - UMONS, S. 252, 2013Kongress: Benelux Meeting on Systems and Control; 32 (Houffalize, Belgium) : 2013.03.26-28

Deterministic global optimization of multistage melt crystallization processes

Kunde, Christian; Müller, C.; Kienle, Achim

In: 2st European Congress of Applied Biotechnology and 9th European Congress of Chemical Engineering, The Hague, The Netherland, April, 21 -25, 2013Kongress: ECCE; 9 (Den Haag, The Netherland) : 2013.04.21-25

An efficient method for calculating the moments of multidimensional growth processes

Dürr, Robert; Kienle, Achim

In: 5th International Conference on Population Balance Modelling. - Banaglore : Indian Institute of Science, insges. 4 S., 2013Kongress: PBM 2013; 5 (Bangalore, India) : 2013.09.11-13

Online parameter identification for continuous fluidized bed spray granulation

Palis, Stefan; Kienle, Achim

In: 5th International Conference on Population Balance Modelling. - Banaglore : Indian Institute of Science, insges. 7 S., 2013Kongress: PBM 2013; 5 (Bangalore, India) : 2013.09.11-13

2012

Book chapter

Discrepancy based control of continuous fluidized bed spray granulation with internal product classification

Palis, Stefan; Kienle, Achim

In: 8th IFAC International Symposium on Advanced Control of Chemical Processes 2012. - Elsevier, S. 756-761Kongress: IFAC International Symposium on Advanced Control of Chemical Processes; 8 (Singapore) : 2012.07.10-13

A plug and control strategy for simulated moving bed processes

Suvarov, Paul; Wouwer, Alain Vande; Kienle, Achim

In: 31st Benelux Meeting on Systems and Control. - disc, S. 343, 2012Kongress: Benelux Meeting on Systems and Control; 31 (Heijden, The Netherlands) : 2012.03.27-29

A simple robust control for simulated moving bed chromatographic separation

Suvarov, Paul; Vande Wouwer, Alain; Kienle, Achim

In: 8th IFAC International Symposium on Advanced Control of Chemical Processes 2012. - Elsevier, S. 137-142Kongress: IFAC International Symposium on Advanced Control of Chemical Processes; 8 (Singapore) : 2012.07.10-13

Low order controller design for continuous fluidized bed spray granulation with internal product classification by robust control methods

Palis, Stefan; Bück, Andreas; Kienle, Achim

In: 7th IFAC Symposium on Robust Control Design: Aalborg Congress & Culture Centre, Denmark, 20 - 22 July 2012 - Elsevier, S. 701-706Kongress: IFAC Symposium on Robust Control Design 7 (Aalbourg, Denmark : 2012.06.20-22)

Peer-reviewed journal article

Systematic evaluation of models of different complexity for a low-density polyethylene plant

Disli, Ilknur; Kienle, Achim

In: Mathematical and computer modelling of dynamical systems. - London [u.a.] : Taylor & Francis, Bd. 18.2012, 4, S. 397-412

Decentralized control system design for a ternary reactive distillation with inert using mixed integer optimization

Paramasivan, Ganesh; Kienle, Achim

In: Chemical engineering & technology. - Weinheim : Wiley-VCH Verl.-Ges, Bd. 35.2012, 9, S. 1609-1616

Auto-tuning of multivariable PID controllers using iterative feedback tuning

Sommer, Steffen; Kienle, Achim

In: Automatisierungstechnik: AT - Berlin: De Gruyter, 1985, Bd. 60.2012, 1, S. 20-27

Dissertation

Model-based measurement and control of fluidised bed spray granulation processes

Bück, Andreas; Tsotsas, Evangelos; Kienle, Achim; Peglow, Mirko

In: Magdeburg, Univ., Fak. für Verfahrens- und Systemtechnik, Diss., 2012, XII, 190 S., Ill., graph. Darst.

Article in conference proceedings

Distributed modeling and parameter estimation of influenza virus replication during vaccine production authors

Dürr, Robert; Müller, Thomas; Isken, Britta; Schulze-Horstel, Josef; Reichl, Udo; Kienle, Achim

In: Preprints MATHMOD 2012 Vienna: abstract volume - Vienna: ARGESIM, ARGE Simulation News, Vienna Univ. of Technology, insges. 6 S. - (ARGESIM report; 38)Kongress: MATHMOD 7 (Vienna : 2012.02.15-17)

Multiscale modeling of biopolymer production in multicellular systems

Franz, Andre; Grammel, Hardy; Rehner, Ruxandra; Paetzold, Philipp; Kienle, Achim

In: MATHMOD 2012. - Vienna : ARGESIM, ARGE Simulation News, Vienna Univ. of Technology, insges. 5 S. - (ARGESIM report; 38)Kongress: MATHMOD; 7 (Vienna) : 2012.02.15-17

Simulation and nonlinear analysis of the stagnant polymer layer in a LDPE tubular reactor

Krasnyk, Mykhaylo; Kunde, Christian; Kienle, Achim

In: Addendum to 22nd European Symposium on Computer Aided Process Engineering. - Amsterdam [u.a.] : Elsevier [u.a.], insges. 5 S., 2012Kongress: European Symposium on Computer Aided Process Engineering, ESCAPE; 22 (London) : 2012.06.17-20

Original article in peer-reviewed international journal

Stabilization of continuous fluidized bed spray granulation with external product classification

Palis, Stefan; Kienle, Achim

In: Chemical engineering science. - Amsterdam : Elsevier, Bd. 70.2012, S. 200-209

Design of an integrated process of chromatography, crystallization and racemization for the resolution of 2',6'-pipecoloxylidide (PPX)

Langermann und Erlencamp, Jan; Kaspereit, Malte; Shakeri, Mozaffar; Lorenz, Heike; Hedberg, Martin; Jones, Matthew Jonathan; Larson, Kerstin; Herschend, Björn; Arnell, Robert; Temmel, Erik; Bäckvall, Jan-E.; Kienle, Achim; Seidel-Morgenstern, Andreas

In: Organic process research & development - Washington, DC : American Chemical Society, Bd. 16 (2012), Heft 2, S. 343-352

Rapid selection of glucose-utilizing variants of the polyhydroxyalkanoate producer Ralstonia eutropha H16 by incubation with high substrate levels

Franz, Andre; Rehner, R.; Kienle, Achim; Grammel, H.

In: Letters in applied microbiology. - Oxford : Wiley-Blackwell, Bd. 54.2012, 1, S. 45-51

Diskrepanzbasierte Regelung der kontinuierlichen Kristallisation

Palis, Stefan; Kienle, Achim

In: Automatisierungstechnik: AT ; Methoden und Anwendungen der Steuerungs-, Regelungs- und Informationstechnik - Berlin: ˜deœ Gruyter, Oldenbourg, 1985, Bd. 60.2012, 3, S. 145-154

Evaluation of competing process concepts for the production of pure enantiomers

Kaspereit, Malte; Swernath, Subramanian; Kienle, Achim

In: Organic process research & development. - Washington, DC : American Chemical Society, Bd. 16.2012, 2, S. 353-363

Decentralized control system design under uncertainty using mixed-integer optimization

Paramasivan, Ganesh; Kienle, Achim

In: Chemical engineering & technology. - Weinheim : Wiley-VCH, Bd. 35.2012, 2, S. 261-271

2011

Original article in peer-reviewed international journal

Experimental validation of a new integrated simulated moving bed process for the production of single enantiomers

Palacios, Javier García; Kramer, Bernhard; Kienle, Achim; Kaspereit, Malte

In: Journal of chromatography. - Amsterdam [u.a.] : ElsevierJournal of chromatography / A, Bd. 1218.2011, 16, S. 2232-2239

A model for the freeze start behavior of a PEM fuel cell stack

Mangold, Michael; Piewek, Silvia; Klein, Olaf; Kienle, Achim

In: Journal of fuel cell science and technology. - New York, NY : ASME, Bd. 8.2011, 3, S. 031006-1-031009

Integrated simulated moving bed processes for production of single enantiomers

Palacios, J. G.; Kaspereit, Malte; Kienle, Achim

In: Chemical engineering & technology. - Weinheim : Wiley-VCH, Bd. 34.2011, 5, S. 688-698

Inferential control of reactive destillation columns - an algorithmic approach

Paramasivan, Ganesh; Kienle, Achim

In: Chemical engineering & technology. - Weinheim : Wiley-VCH, Bd. 34.2011, 8, S. 1235-1244

Iterative feedback tuning of PID controllers for reactive distillation processes - a comparison with relay feedback tuning

Sommer, Steffen; Müller, Peter; Kienle, Achim

In: Industrial & engineering chemistry research. - Washington, DC : American Chemical Society, Bd. 50.2011, 16, S. 9821-9828

Experimental and theoretical analysis of poly(ß-hydroxybutyrate) formation and consumption in Ralstonia eutropha

Franz, André; Song, Hyun-Seob; Ramkrishna, Doraiswami; Kienle, Achim

In: Biochemical engineering journal. - Amsterdam [u.a.] : Elsevier Science, Bd. 55.2011, 1, S. 49-58

Model-based measurement of particle size distributions in layering granulation processes

Bück, Andreas; Peglow, Mirko; Tsotsas, Evangelos; Mangold, Michael; Kienle, Achim

In: AIChE journal. - Hoboken, NJ : Wiley-Blackwell, Bd. 57.2011, 4, S. 929-941

Original article in peer-reviewed periodical-type series

Population balance modelling of influenza virus replication during vaccine production - influence of apoptosis

Müller, Thomas; Dürr, Robert; Isken, Britta; Schulze-Horsel, Josef; Reichl, Udo; Kienle, Achim

In: 21st European Symposium on Computer Aided Process Engineering ; Pt. B. - Amsterdam [u.a.] : Elsevier, S. 1336-1340, 2011 - (Computer-aided chemical engineering; 29)Kongress: ESCAPE; 21 (Chalkidiki, Greece) : 2011.05.29-06.01

Towards global optimization of combined distillation-crystallization processes for the separation of closely boiling mixtures

Ballerstein, Martin; Kienle, Achim; Kunde, Christian; Michaels, Dennis; Weismantel, Robert

In: 21st European Symposium on Computer Aided Process Engineering ; Pt. A. - Amsterdam [u.a.] : Elsevier, S. 552-556, 2011 - (Computer-aided chemical engineering; 29)Kongress: ESCAPE; 21 (Chalkidiki, Greece) : 2011.05.29-06.01

2010

Book chapter

Decentralized control system design using mixed integer optimization

Paramasivan, Ganesh; Kienle, Achim

In: Book of abstracts and CD-ROM proceedings // EngOpt 2010, 2nd International Conference on Engineering Optimization. - Lisboa : APMTAC, Associação Portuguesa de Mecânica Teórica, Aplicada e Computacional, insges. 10 S.Kongress: EngOpt 2010; 2 (Lisboa, Portugal) : 2010.09.06-09

Model-based measurement of PSDs granulation processes

Bück, Andreas; Peglow, Mirko; Tsotsas, Evangelos; Kienle, Achim

In: Abstracts and proceedings // WCPT6-2010, World Congress on Particle Technology. - Nürnberg, insges. 4 S.Kongress: WCPT; 6 (Nürnberg) : 2010.04.26-29[Beitrag auf CD-ROM]

Model-based measurement and control of particulate processes - an application to granulation processes

Bück, Andreas; Peglow, Mirko; Tsotsas, Evangelos; Mangold, M.; Kienle, Achim

In: 19th International Congress of Chemical and Process Engineering and 7th European Congress of Chemical Engineering. - Praha, insges. 11 S., 2010Kongress: CHISA 2008; 19 (Praha, Czech Republic) : 2010.08.28-09.01[Beitrag auf CD-ROM]

Article in conference proceedings

Stabilization of a continuous fluidized bed spray granulation

Palis, Stefan; Kienle, Achim

In: 4th International Conference on Population Balance Modelling. - Berlin : Max-Planck-Institut für Dynamik komplexer technischer Systeme, S. 87-97, 2010Kongress: PBM 2010; 4 (Berlin) : 2010.09.15-17

Original article in peer-reviewed international journal

Temperature and humidity control of a micro PEM fuel cell stack

Kunde, Christian; Hanke-Rauschenbach, R.; Mangold, Michael; Kienle, Achim; Sundmacher, Kai; Wagner, S.; Hahn, R.

In: Fuel Cells. - Weinheim : Wiley-VCH, Bd. 10.2010, 6, S. 949-959

Reduction procedure for parametrized fluid dynamics problems based on proper orthogonal decomposition and calibration

Krasnyk, Mykhaylo; Mangold, Michael; Kienle, Achim

In: Chemical engineering science. - Amsterdam : Elsevier, Bd. 65.2010, 23, S. 6238-6246

Inline chemical process analysis in micro-plants based on thermoelectric flow and impedimetric sensors

Jacobs, Thomas; Kutzner, Christian; Kropp, Miron; Brokmann, Geert; Lang, Walter; Steinke, Arndt; Kienle, Achim; Hauptmann, Peter

In: Measurement science and technology. - Bristol : IOP Publ. Ltd, Bd. 21.2010, 10, insges. 12 S.

Capillary type thermal mass flow sensors for monitoring esterification reactions in residence time micro-reactors

Jacobs, Thomas; Kienle, Achim; Hauptmann, Peter

In: Chemical engineering journal. - Amsterdam : Elsevier, Bd. 160.2010, 3, S. 827-833

Original article in peer-reviewed periodical-type series

Regelung von Brennstoffzellensystemen

Mangold, Michael; Kienle, Achim

In: Jahresbericht // Max-Planck-Gesellschaft zur Förderung der Wissenschaften. - München : Max-Planck-Ges, insges. 7 S., 2010

A reactive distillation case study for decentralized control system design using mixed integer optimization

Paramasivan, Ganesh; Kienle, Achim

In: 20th European Symposium on Computer Aided Process Engineering. - Amsterdam [u.a.] : Elsevier, S. 565-570, 2010Kongress: ESCAPE; 20 (Ischia) : 2010.06.06-09

Energy management for heat intensive production plants using mixed integer optimization

Sommer, Steffen; Böhm, Jens; Kienle, Achim

In: 20th European Symposium on Computer Aided Process Engineering. - Amsterdam [u.a.] : Elsevier, S. 877-882, 2010Kongress: ESCAPE; 20 (Ischia) : 2010.06.06-09

2009

Book chapter

A model based analysis of multiple steady states in continuous cell cultures

Disli, Ilknur; Kremling, A.; Kienle, Achim

In: Proceedings // MATHMOD 09. - Vienna : ARGESIM, Publ. House, S. 796-804, 2009 - (ARGESIM report; 35)Kongress: MATHMOD; 6 (Vienna) : 2009.02.11-13

Hybrid cybernetic modeling of poly-β-hydroxybutyrate synthesis and degradation in cupriavidus necator

Franz, André; Song, Hyun-Seob; Kienle, Achim; Ramkrishna, Doraiswami

In: Food, pharmaceutical and bioengineering division. - New York : AIChE, S. 118-126, 2009Kongress: AIChE Annual Meeting; : (Nashville, Tennessee) : 2009.11.08-13

Dynamic modeling and simulation of low density polyethylene production - a comparative study

Disli, Ilknur; Kienle, Achim

In: Proceedings // MATHMOD 09. - Vienna : ARGESIM, Publ. House, S. 2372-2378, 2009 - (ARGESIM report; 35)Kongress: MATHMOD; 6 (Vienna) : 2009.02.11-13

Original article in peer-reviewed international journal

Dynamics of reactive distillation processes with potential liquid phase splitting based on equilibrium stage models

Radulescu, Gabriel; Gangadwala, Jignesh; Paraschiv, Nicolae; Kienle, Achim; Sundmacher, Kai

In: Computers & chemical engineering. - Amsterdam [u.a.] : Elsevier, Bd. 33.2009, 3, S. 590-597

Conceptual analysis of the effect of kinetics on the stability and multiplicity of a coupled bioreactor-separator system using a cybernetic modeling approach

Kumar, M. Vasudeva; Zeyer, K. P.; Kienle, Achim; Pushpavanam, S.

In: Industrial & engineering chemistry research. - Washington, DC : American Chemical Society, Bd. 48.2009, 24, S. 10962-10975

Combination of a novel perforated thermoelectric flow and impedimetric sensor for monitoring chemical conversion in micro fluidic channels

Jacobs, Thomas; Kutzner, Christian; Kropp, M.; Brokmann, G.; Lang, W.; Steinke, A.; Kienle, Achim; Hauptmann, Peter

In: Procedia chemistry. - Amsterdam [u.a.] : Elsevier, Bd. 1.2009, 1, S. 1127-1130[Proceedings of the Eurosensors XXIII Conference]

Novel pressure stable thermoelectric flow sensor in non-steady state operation mode for inline process analysis in micro reactors

Jacobs, Thomas; Kutzner, Christian; Kropp, M.; Lang, W.; Kienle, Achim; Hauptmann, Peter

In: Procedia chemistry. - Amsterdam [u.a.] : Elsevier, Bd. 1.2009, 1, S. 148-151[Proceedings of the Eurosensors XXIII Conference]

Conceptual design of integrated chromatographic processes for the production of single (stereo-)isomers

Garcia Palacios, Javier; Kaspereit, Malte; Kienle, Achim

In: Chemical engineering & technology. - Weinheim : Wiley-VCH, Bd. 32.2009, 9, S. 1392-1402

Analysis of the coupling behavior of PEM fuel cells and DC-DC converters

Grötsch, Markus; Mangold, Michael; Kienle, Achim

In: Energies. - Basel : MDPI, Bd. 2.2009, 1, S. 71-96

Original article in peer-reviewed national journal

Ein Energie-Management-System für wärmeintensive Produktionsprozesse

Sommer, Steffen; Böhm, Jens; Kienle, Achim

In: Automatisierungstechnik: AT ; Methoden und Anwendungen der Steuerungs-, Regelungs- und Informationstechnik - Berlin: ˜deœ Gruyter, Oldenbourg, 1985, Bd. 57.2009, 11, S. 578-585

Original article in peer-reviewed periodical-type series

Novel impedimetric and perforated thermal flow sensor for inline chemical process analysis in micro residence time reactors

Jacobs, Thomas; Kutzner, C.; Kropp, M.; Brokmann, G.; Lang, W.; Steinke, A.; Kienle, Achim; Hauptmann, Peter

In: IEEE Sensors 2009. - IEEE, S. 719-722Kongress: IEEE Conference on Sensors; 8 (Christchurch) : 2009.10.25-28[Auch auf CD-ROM erschienen]

2008

Book chapter

Energie-Management-System für einen Produktionsbetrieb

Sommer, Steffen; Böhm, Jens; Kienle, Achim

In: Entwurf komplexer Automatisierungssysteme, EKA 2008 - Beschreibungsmittel, Methoden, Werkzeuge und Anwendungen ; 10. Fachtagung, 15. bis 16. April 2008 Tutorium, 16. bis 17. April 2008 Fachtagung, Magdeburg, Denkfabrik im Wissenschaftshafen: Beschreibungsmittel, Methoden, Werkzeuge und Anwendungen ; 10. Fachtagung, 15. bis 16. April 2008 Tutorium, 16. bis 17. April 2008 Fachtagung, Magdeburg, Denkfabrik im Wissenschaftshafen - Magdeburg: Univ., 2008; Jumar, Ulrich . - 2008, S. 109-120Kongress: Fachtagung 10 (Magdeburg : 2008.04.15-17)

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